Neisseria meningitidis in urogenital infection.

Neisseria Meningitides in Urogenital Infection.

Transcriptome analysis of Neisseria meningitidis during infection.

Neisseria meningitidis is the cause of septicemia and meningococcal meningitis. During the course of infection, N. meningitidis encounters multiple environments within its host, which makes rapid adaptation to environmental changes a crucial factor for neisserial pathogenicity. Employing oligonucleotide-based DNA microarrays, we analyzed the transcriptome of N. meningitidis during two key steps...

Iron-controlled infection with Neisseria meningitidis in mice.

An iron-controlled infection was obtained after the intraperitoneal infection of Neisseria meningitidis strain M1011 into normal mice. The infection progressed rapidly but then disappeared in concert with the disappearance of plasma transferrin iron. Parenteral iron dextran enhanced and prolonged the infection in mice at dosages above 15 mg of Fe per kg. Studies on the distribution of iron dext...

Extrameningeal complications of Neisseria meningitidis serogroup W135 infection.

Received 3 March 2004; accepted 4 March 2004; electronically published 12 May 2004. Reprints or correspondence: Dr. Michael A. Apicella, Dept. of Microbiology, University of Iowa, 51 Newton Rd., Iowa City, IA 52242 ([email protected]). Clinical Infectious Diseases 2004; 38:1638–9 2004 by the Infectious Diseases Society of America. All rights reserved. 1058-4838/2004/3811-0023$15.00 Nei...

Travel-related Neisseria meningitidis Serogroup W135 Infection, France

ICU (median age 1.2 years; p<0.001, Mann-Whitney U test). An exploratory logistic regression analysis on ICU admittance, adjusted for age, confirmed a strong association between RSV genotype ON1 and ICU admittance (adjusted odds ratio 8.4; 95% CI 1.5%–46.6%; p = 0.015). However, this significant difference should be interpreted with caution for 2 reasons: 1) samples from patients in wards other...